Friday, July 25, 2008

Humira: Got Rheumatoid Arthritis?

ABOUT: Rheumatoid arthritis can cause joint damage, as seen on x-ray, within the first year. For many people, HUMIRA can help slow the progression of that damage.

HUMIRA is a TNF Blocker.

TNF (tumor necrosis factor) [TNF is a protein messenger produced by the body's immune cells that yells "hey you guys, get in here, we have a problem here" It tells the rest of the immune cells that there is a problem and to react] blockers are a class of medications that fight both the painful symptoms and progressive joint damage of moderate to severe rheumatoid arthritis.

TNF blockers can slow down the rate at which RA causes damage to joints and bones. HUMIRA is one such TNF blocker.

For many patients, HUMIRA can provide relief to painful joints. It can help fight the fatigue. And it can help slow the progressive joint damage of moderate to severe rheumatoid arthritis.

BLAH! How does it work?

Humira is a monoclonal human antibody against the cytokine TNF (see above). It binds to circulating TNF in the blood and binds to it, thereby inactivating it. It therefore cannot bind to its receptor, thus inhibiting it's RA effects.

There are more indications for Humira other than RA, and I will post them here.

Your poster has a broken foot, and the vicodin is working in full effect. More to follow......More tomorrow. Good night.

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