current times

I will update this page daily, so many new things that need to be explained.
Recently laid off from my job, I have plenty of time to keep the site updated.

Indometacin...

I found out that I have gout in my big toe. OUCH!!!
I was given indometacin:

To give you a trailer: it's a NSAID on steroids! Sorry PUN intended, it's not a steriod but it's a strong one.
I'm back to posting so i'll update this tomorrow, I have so much information for you about all these new drugs. Drug a day, post away......

Back!

I've been sick and now i'm back. There are a lot of new drugs out there that we need to know about. I'M BAAACK.!

stay tuned. thanks.

Let's hope Humira works: Here's what RA does to your hands

Humira: Got Rheumatoid Arthritis?

ABOUT: Rheumatoid arthritis can cause joint damage, as seen on x-ray, within the first year. For many people, HUMIRA can help slow the progression of that damage.

HUMIRA is a TNF Blocker.

TNF (tumor necrosis factor) [TNF is a protein messenger produced by the body's immune cells that yells "hey you guys, get in here, we have a problem here" It tells the rest of the immune cells that there is a problem and to react] blockers are a class of medications that fight both the painful symptoms and progressive joint damage of moderate to severe rheumatoid arthritis.

TNF blockers can slow down the rate at which RA causes damage to joints and bones. HUMIRA is one such TNF blocker.

For many patients, HUMIRA can provide relief to painful joints. It can help fight the fatigue. And it can help slow the progressive joint damage of moderate to severe rheumatoid arthritis.

BLAH! How does it work?

Humira is a monoclonal human antibody against the cytokine TNF (see above). It binds to circulating TNF in the blood and binds to it, thereby inactivating it. It therefore cannot bind to its receptor, thus inhibiting it's RA effects.

There are more indications for Humira other than RA, and I will post them here.

Your poster has a broken foot, and the vicodin is working in full effect. More to follow......More tomorrow. Good night.

Humira

Along with the staff at biotech1o1, we were at Del Mar today and we are still scratching our heads as to why we like to bet longshot trifectas and still think there is a shot to win. We think a post in the am when we can think straight, is due on Humira. Stay tuned, thanks.

This one's for Mom: Gemfibrozil (Lopid)

Ms. Field, i'll get back to you tomorrow.

My Mom was just put on yet another cholesterol lowering drug, as probably many of you have too have been on the merry-go-round to prescription drugs. So let's go through what this drug is, it's chemical nature and history and how it works:

Gemfibrozil belongs to a class of drugs used in hyperlipidemia (HL), which is basically elevated levels of fats in the blood. Decisions to use drug therapy for HL must be based on the potential for causing atherosclerosis or pancreatitis. Most important, diet of the individual is a necessary co-therapy to drug therapy and should be followed strictly to achieve the full potential of drug therapy.

Gemfibrozil is a first generation fibric acid derivative clofibrate. First generation means that this is an older drug and it works by making an enzyme that causes fats to be cut up at a higher rate.

Gemfibrozil is thought to function by binding to a DNA binding protein called PPAR [called a transcription factor]. It increases fat cutting enzymes that degrade triglycerides.

Skin rashes, intestinal symptoms, heart palpitations are associated with toxicity. It seems it increases the mechanism of action of blood thinning drugs as well.

Take it in good health Mom! LU!